A survey of blockholders and corporate control

The author surveys the empirical literature on large-percentage shareholders in public corporations, focusing on four key issues: the prevalence of blockholders; the motivation for block ownership; the effect of blockholders on executive compensation, leverage, the incidence of takeovers, and a wide range of corporate decisions; and the effect of blockholders on firm value. A central finding of this study is that there is little reason for policymakers or small investors to fear large-percentage shareholders in general, especially when the blockholders are active in firm management.Stockholders ; Corporate governance

Mothering at a distance and disclosure of maternal HIV to children in Kingston, Jamaica

Accepted for publication in a forthcoming issue of Population Horizons, an open access peer-reviewed journal by The Oxford Institute of Population Ageing.Existing guidelines (WHO, 2011) advise caretakers and professionals to disclose children’s and their caretakers’ HIV status to children, despite a lack of evidence concerning the potential implications in resource-constrained settings. Our research uses feminist Interpretative Phenomenological Analysis (IPA) to explore the experiences of HIV positive mothers in Kingston, Jamaica, focusing on their lived experiences of talking to their children about maternal HIV. This paper will focus on the concept of mothering at a distance and how this presents additional challenges for HIV positive mothers who are trying to establish emotional closeness in relation to talking to their children about their HIV. Using Hochschild’s concept of emotion work and examples from the interviews, we highlight the difficult contexts informing women’s decisions when negotiating discussions about their HIV. Women may choose full, partial or differential disclosure or children may be told their mother’s HIV status by others. Disclosure policy, we argue, reflects Anglo-Northern constructions of the family and parenting which may not adequately reflect the experiences of poor urban mothers in low and middle income countries. We argue that policy needs to recognise culturally-specific family formations, which, in Jamaica includes absent fathers, mothering at a distance and mothering non-biological children. This article reflects on the experiences of an under-researched group, poor urban Jamaican women practising mothering at a distance, using a novel methodological approach (IPA) to bring into relief unique insights into their lived experiences and will contribute to the global policy and research literature on HIV disclosure. Keywords: Feminist IPA, HIV disclosure, mothering, emotion workPeer reviewedFinal Accepted Versio

Universality in the Large N_c Dynamics of Flavour: Thermal Vs. Quantum Induced Phase Transitions

We show how two important types of phase transition in large N_c gauge theory with fundamental flavours can be cast into the same classifying framework as the meson-melting phase transition. These are quantum fluctuation induced transitions in the presence of an external electric field, or a chemical potential for R-charge. The classifying framework involves the study of the local geometry of a special D-brane embedding, which seeds a self-similar spiral structure in the space of embeddings. The properties of this spiral, characterized by a pair of numbers, capture some key universal features of the transition. Computing these numbers for these non-thermal cases, we find that these transitions are in the same universality class as each other, but have different universal features from the thermal case. We present a natural generalization that yields new universality classes that may pertain to other types of transition.Comment: 22 pages, 4 figures, pdfLaTe

Russia's FLat-Tax: Myths and facts

Flat Tax, Russland, Russia

Precessing supermassive black hole binaries and dark energy measurements with LISA

Spin induced precessional modulations of gravitational wave signals from supermassive black hole binaries can improve the estimation of luminosity distance to the source by space based gravitational wave missions like the Laser Interferometer Space Antenna (LISA). We study how this impacts the ablity of LISA to do cosmology, specifically, to measure the dark energy equation of state (EOS) parameter $w$. Using the $\Lambda$CDM model of cosmology, we show that observations of precessing binaries by LISA, combined with a redshift measurement, can improve the determination of $w$ up to an order of magnitude with respect to the non precessing case depending on the masses, mass ratio and the redshift.Comment: 4 pages, 4 figures, version accepted to PR

Minimum Bias Legacy of Search Results

The end of LEP and SLC is a good moment to review the way to summarize search results in order to exploit at best, in future analyses and speculations, the pieces of information coming from all experiments. Some known problems with the usual way of reporting results in terms ``CL limits'' are shortly recalled, and a plea is formulated to publish just parametrized likelihoods, possibly rescaled to the asymptotic insensitivity limit level.Comment: Talk given at the Seventh Topical Seminar on ``The legacy of LEP and SLC '', Siena, Italy, 8-11 October 2001. This paper and related work are also available at http://www-zeus.roma1.infn.it/~agostini/prob+stat.htm

Presentations of higher dimensional Thompson groups

In a previous paper, we defined a higher dimensional analog of Thompson's group V, and proved that it is simple, infinite, finitely generated, and not isomorphic to any of the known Thompson groups. There are other Thompson groups that are infinite, simple and finitely presented. Here we show that the new group is also finitely presented by calculating an explicit finite presentation.Comment: 35 pages, to appear in J. Algebr

Identification of integrin drug targets for 17 solid tumor types.

Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility. In solid tumors, integrins are involved in promoting metastasis to distant sites, and angiogenesis. Integrins are a key target in cancer therapy and imaging. Integrin antagonists have proven successful in halting invasion and migration of tumors. Overexpressed integrins are prime anti-cancer drug targets. To streamline the development of specific integrin cancer therapeutics, we curated data to predict which integrin heterodimers are pausible therapeutic targets against 17 different solid tumors. Computational analysis of The Cancer Genome Atlas (TCGA) gene expression data revealed a set of integrin targets that are differentially expressed in tumors. Filtered by FPKM (Fragments Per Kilobase of transcript per Million mapped reads) expression level, overexpressed subunits were paired into heterodimeric protein targets. By comparing the RNA-seq differential expression results with immunohistochemistry (IHC) data, overexpressed integrin subunits were validated. Biologics and small molecule drug compounds against these identified overexpressed subunits and heterodimeric receptors are potential therapeutics against these cancers. In addition, high-affinity and high-specificity ligands against these integrins can serve as efficient vehicles for delivery of cancer drugs, nanotherapeutics, or imaging probes against cancer